The Best Boutique Hotels To Book In Panama City

Panama City is a city of contrasts. With historical buildings on one side and ultramodern skyscrapers on the other, its architecture is a true melting pot. So whether you’re looking for artsy décor or for the classic charm of a grand hotel, our guide has got you covered. Check out the best boutique hotels in Panama City and find the perfect spot to enjoy a tropical getaway.

Hotel Casa Panamá

Boutique Hotel, Hotel

Casa Panama is a design boutique hotel located in Casco Viejo which brings together modern aesthetics and natural materials to create a unique space that includes a restaurant, a bar and a nightclub.

Tantalo Hotel / Kitchen / Rooftop

Boutique Hotel, Hotel

Tantalo Hotel / Kitchen / Rooftop is one of the trendiest boutique hotels in Casco Viejo. Famous not only for its uniquely designed rooms but also for one of Panama City’s most visited rooftop bars, it is an unavoidable pit-stop when visiting (or living) in Panama City.

The Bristol Hotel

Boutique Hotel, Hotel

Aerial view of the outdoor pool at Bristol Hotel, Panama City, with a woman swimming

One of the very best places to stay in Panama City, the Bristol is a luxurious contemporary boutique hotel located right in the heart of the financial district in Obarrio. With a gourmet restaurant and a spa center, the hotel truly offers world-class service.

American Trade Hotel

Hotel

Both a boutique luxury hotel and an events space, the American Trade Hotel is one of the most elegant and sought-after destinations in Panama City. Located in a beautiful 1917 building, it breathes local heritage and culture while meeting the needs of contemporary travelers.

Global Hotel Panama

Boutique Hotel, Hotel

Global Hotel Panama is an exclusive, privately-owned luxury boutique hotel that promises elegance, simplicity and supreme service. With an outdoor swimming pool, the hotel is a romantic retreat within the hectic neighborhood of Obarrio.

Central Hotel Panamá

Boutique Hotel, Hotel

Exterior of Central Hotel in Panama City showing windows and balconies

Central Hotel Panamá is a luxury Panama City boutique hotel located in a renovated colonial building featuring a unique French-influenced design. Surrounded by some of the best views, restaurants, cafés, bars and art galleries of Panama City, the hotel captures the historic spirit of Casco Viejo.