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© Hotel Casa Panamá
© Hotel Casa Panamá

The Best Boutique Hotels in Panama City

Picture of Martina Gili
Updated: 14 September 2017

Panama City is a city of contrasts. With historical buildings on one side and ultramodern skyscrapers on the other, its architecture is a true melting pot. So whether you’re looking for artsy décor or for the classic charm of a grand hotel, our guide has got you covered. Check out the best boutique hotels in Panama City and find the perfect spot to enjoy a tropical getaway.


Hotel Casa Panamá

Casa Panama is a design boutique hotel located in Casco Viejo which brings together modern aesthetics and natural materials to create a unique space that includes a restaurant, a bar and a nightclub.

Avenida Eloy Alfaro and Calle 11, Panama CityPanama +507 303-0992

Hotel Casa Panamá, Casco Viejo | © Courtesy of Hotel Casa Panamá


Tantalo Hotel / Kitchen / Rooftop

Tantalo Hotel / Kitchen / Rooftop is one of the trendiest boutique hotels in Casco Viejo. Famous not only for its uniquely designed rooms but also for one of Panama City’s most visited rooftop bars, it is an unavoidable pit-stop when visiting (or living) in Panama City.

Calle 8 Este and Avenida B, Panama City, Panama +507 262-4030

© Wu Yi/ Unsplash


The Bristol Hotel

Often rated as the best hotel in town, the Bristol is a luxurious contemporary boutique hotel located right in the heart of Panama City’s financial district in Obarrio. With a gourmet restaurant and a spa center, the hotel truly offers world-class service.

Ave. Aquilino de la Guardia, Panama City, Panama +507 264-0000

The pool, Bristol Hotel, Panama City © Bristol Hotel


American Trade Hotel

Both a boutique luxury hotel and an events space, the American Trade Hotel is one of the most elegant and sought-after destinations in Panama City. Located in a beautiful 1917 building, it breathes local heritage and culture while meeting the needs of contemporary travelers.

Av. Central, Panama City, Panama +507 831-2051

© American Trade Hotel Panama

Global Hotel Panama

Global Hotel Panama is an exclusive, privately-owned luxury boutique hotel that promises “elegance, simplicity and supreme service”. With an outdoor swimming pool, the hotel is a romantic retreat within the hectic neighborhood of Obarrio.

Calle 54 Este and Samuel Lewis, Panama City, Panama +507 280-6400

Outdoor pool at Global Hotel Panama © Global Hotel Panama

Central Hotel Panamá

Central Hotel Panamá is a luxury boutique hotel located in a renovated colonial building featuring a unique French-influenced design. Surrounded by some of the best views, restaurants, cafés, bars and art galleries of Panama City, the hotel captures the historic spirit of Casco Viejo.

Plaza de la Independencia, Calle 5a Este, Panama City, Panama +507 309-0300

Central Hotel, Panama City © Central Hotel