Grand Hotel Imperiale & Resort, Lombardy

Channel “locals” George and Amal Clooney at this opulent Lake Como pile, all white marble floors, gourmet fish feasts and million-dollar views. Cream-hued rooms with herringbone floors come, in some cases, with balconies for sunny brunches, while the spa is a serene retreat, with a detoxifying salt room. Snag a lounger at the garden-fringed pool and watch the Como glitterati zip across the lake on private boats or water-skis.