Great River Road National Scenic Byway
Known more prosaically as Highway 35, this road trip is a 250mi (402km) drive along the Mississippi River. If you’re paying attention on the way, you might even be able to spell Mississippi by the end of the trip. Stretching from Prescott to Potosi, this drive has 33 charmingly small and quaint towns to visit along the way, many with art galleries, wineries and historic sites of interest to draw your attention. Pull up your best road trip playlist and get going.