The concert will take place on September 23 in New York’s Central Park.
Pharrell Williams, Big Sean, Andra Day, the Killers, the Lumineers and Alessia Cara will also be performing at the sixth annual event with more special guests to be announced in the coming weeks.
Wonder said in a statement: ‘In this crucial time, there is nothing more exciting to me than having the honor of giving my gift of song, words and motivation to the Global Citizen Festival.
‘When we commit ourselves to life issues, we are showing love of the Most High. I was, I am and will always be, a citizen connected to the spirit of everyone on this planet moving forward. Let’s go!’
The festival is free of charge with 60,000 tickets to be given away.
Music fans must first participate in Global Citizen’s initiatives to end extreme poverty worldwide by signing petitions or tweeting messages at world leaders first before they are entered into a lottery.
‘We’re grateful to be a part of this year’s Global Citizen Festival,’ Green Day singer Billie Joe Armstrong added.
‘American aid programs make a significant difference in the betterment of lives at home and around the world, and we should all want these programs to become stronger, not weaker. We all play a part in seeing this mission through and it starts with calling on all our leaders.’
Global Citizen asks participants to hold world leaders accountable on issues like education, food security, healthcare, gender equality, and sanitation.
The organisation also aims to ‘end poverty, tackle climate change and fight inequalities by 2030’.