The 5 Best Hotels in the Mission, San Francisco

The Mission district is one of San Francisco's most vibrant neighborhoods
The Mission district is one of San Francisco's most vibrant neighborhoods | © lechatnoir / Getty Images
San Francisco’s Mission District is full of characterful hotels housed in former movie theaters, Victorian buildings and reimagined motor lodges.

A diverse neighborhood with Latino roots, the Mission District is drenched in a rainbow of swirling murals, neon-lit nightclubs and the Neapolitan shades of its long-standing ice cream parlors. Eclectic vintage stores, independent bookshops and hip coffee bars jostle for your attention, and these hotels perfectly capture the area’s famously artistic vibe.

Inn San Francisco

Bed and Breakfast
Courtesy of Inn San Francisco / Expedia

Built in the 1870s, this 27-room bed and breakfast evokes the Victorian Age in San Francisco. Marble fireplaces and built-in, late 19th-century furniture adds warmth – there’s even one room with a four-poster bed. But the real draws here are the sunny back patio and hot tub, an addition from the later, less restrained era in San Francisco’s history.

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Beck's Motor Lodge

Boutique Hotel, Motel
Courtesy of Beck's Motor Lodge / Expedia

A recently renovated former motor lodge, this low-slung accommodation on Mission’s northern end edges onto the Castro neighborhood. Free on-site parking is a big plus, as is access to the regular streetcar service along Market Street. Modern touches, such as deep-tub sinks in the private bathrooms and flat-screen TVs in the amply proportioned rooms, are sweet. One of the rooms even has a built-in working fireplace.

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Noe's Nest

Bed and Breakfast
Courtesy of Noe's Nest / Expedia

With classic Victorian details inside and out, this bed and breakfast situated on the edge of the Mission near the Noe Valley neighborhood offers the best of both worlds: easy access to the Mission and a quiet, comfortable place to rest your head. One room even opens directly onto the well-maintained garden.

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Nineteen 06 Mission

Eco Hotel
Nineteen 06 Mission, San Francisco
Courtesy of Nineteen 06 Mission / Booking.com

Renovated in 2014, this petite hotel is as modern as they come with eco-toiletries, sustainably sourced towels and locally made bagels at breakfast. Exposed brick and wood finishes add pizzazz to hallways and rooms. Shared bathroom spaces have rainforest showers. White noise machines are provided in each room to dampen the energetic musings of the neighborhood’s nightlife, a feature of the hotel’s proximity to the 16th Street BART.

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San Francisco Proper

Hotel, Boutique Hotel
Deluxe King Rooms feature contemporary decor and plush king-size beds, Proper Hotel
Courtesy of San Francisco Proper Hotel
Located a little northeast of the Mission toward the Civic Center area, the San Francisco Proper hotel resides in a landmark flatiron building built in 1909. Inside the striking red brick-with-emerald-cornicing exterior, you’ll find white pillars and lofty ceilings elevated by gallery walls of abstract art and a mismatch of patterned furniture. The rest of the hotel is similarly wonderland-esque with a subterranean gym and a rare San Francisco rooftop bar, decked out with floral lip-shaped sofas. Grab an Aperol-infused Afternoon Spritz and admire views of the Ferry Building’s clock tower before heading back to a room with a plush handmade mattress, bucolic wallpaper and a minibar stocked with local craft beer, wine and chocolate.
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Chloe Byrne contributed additional reporting to this article.

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These recommendations were updated on August 3, 2020 to keep your travel plans fresh.