La Botica
This stalwart mezcalería has a grand total of six locations across the capital which makes it both convenient and reliable. However, we recommend heading to one of the two Condesa branches as you can enjoy your tipple in some suitably hipster yet upscale surroundings, with minimal interior decor but a pleasingly extensive mezcal menu. There are around 50 mezcals on offer, but do try the exquisite flagship brand.